Source: BEFREE
| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.600 | None | 0.985 | 263 | 3 | 1985 | 2020 | ||||||||
|
SMAD family member 4 | 0.401 | 0.808 | 1.00 |
|
disease | 0.600 | None | 1.000 | 79 | 0 | 1996 | 2020 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.100 | None | 1.000 | 64 | 0 | 1997 | 2020 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 60 | 2 | 2003 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.100 | None | 1.000 | 57 | 0 | 2003 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | 0.320 | 0.885 | 1.4E-06 |
|
disease | 0.100 | None | 1.000 | 55 | 2 | 2003 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | 0.322 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 52 | 1 | 2003 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | 0.319 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 52 | 0 | 2003 | 2020 | ||||||||
|
CD274 molecule | 0.324 | 0.923 | 1.9E-02 |
|
disease | 0.100 | None | 1.000 | 41 | 0 | 2014 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.400 | None | 0.976 | 40 | 0 | 2002 | 2020 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.600 | None | 1.000 | 37 | 1 | 1997 | 2020 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.100 | None | 1.000 | 35 | 1 | 2003 | 2020 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.400 | None | 1.000 | 31 | 0 | 1998 | 2020 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.500 | None | 0.903 | 30 | 1 | 2009 | 2020 | ||||||||
|
epidermal growth factor | 0.357 | 0.923 | 8.5E-17 |
|
disease | 0.100 | None | 1.000 | 29 | 0 | 1986 | 2020 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.100 | None | 1.000 | 29 | 0 | 2001 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.400 | None | 0.900 | 29 | 0 | 1995 | 2020 | ||||||||
|
matrix metallopeptidase 2 | 0.333 | 0.923 | 0.84 |
|
disease | 0.400 | None | 1.000 | 28 | 0 | 1995 | 2020 | ||||||||
|
CEA cell adhesion molecule 5 | 0.420 | 0.846 | 4.2E-10 |
|
disease | 0.100 | None | 1.000 | 25 | 0 | 1998 | 2020 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.400 | None | 0.955 | 21 | 0 | 2002 | 2020 | ||||||||
|
zinc finger E-box binding homeobox 1 | 0.442 | 0.808 | 0.97 |
|
disease | 0.100 | None | 1.000 | 20 | 0 | 2009 | 2020 | ||||||||
|
Yes associated protein 1 | 0.432 | 0.808 | 1.00 |
|
disease | 0.100 | None | 1.000 | 19 | 0 | 2006 | 2020 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
disease | 0.400 | None | 1.000 | 17 | 2 | 2004 | 2020 | ||||||||
|
cyclin dependent kinase 4 | 0.412 | 0.808 | 6.3E-02 |
|
disease | 0.100 | None | 0.867 | 15 | 1 | 1997 | 2020 | ||||||||
|
CD82 molecule | 0.507 | 0.731 | 1.3E-08 |
|
disease | 0.100 | None | 1.000 | 15 | 0 | 1996 | 2020 |